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Next Generation Sequencing

Epistem's Comprehensive Sequencing Options and Specialised Data Analysis Services

Epistem is a leading provider of Next Generation Sequencing (NGS) services that specialise in analysing DNA and RNA samples. Our NGS technique is a powerful tool that enables researchers to obtain accurate and in-depth information about their samples, thereby enhancing the quality of their studies.

What's Available

Sequencing Options for DNA and RNA Samples: Expert Analysis and Illumina NGS Platforms

Our team of experts is highly experienced in analysing various sample types and low input amounts, and we utilise Illumina NGS platforms to offer a wide range of sequencing options for DNA and RNA samples. For DNA samples, we offer whole exome sequencing (WES) and custom targeted sequencing, which have become increasingly popular due to their ability to detect rare and novel variants and sequence samples with a much higher coverage.

Epistem’s sequencing options include:

  • Whole genome sequencing
  • RNA-sequencing
  • Whole exome sequencing
  • TCR-Seq
  • Targeted resequencing (commercially available assays and customised assays)
  • Multiple disease panels available
  • Microbiome analysis

For RNA samples, we offer whole transcriptome sequencing and small RNA sequencing to assess changes in gene expression. Moreover, we provide T cell receptor profiling through targeted RNA sequencing panels.

For customers interested in investigating bacterial diversity in a given sample, we also offer microbiome sequencing.

Data Analysis

At Epistem, we understand that analysing Next Generation Sequencing (NGS) data is just as critical as generating it. That’s why we offer dedicated bioinformatic analysis services tailored to your specific research needs.

Our team of experts can conduct unbiased interrogation of genes that are differentially expressed between relevant comparison groups, followed by comprehensive statistical analysis and ANOVAs based on group experimental factors. We also specialise in focused analysis of genes or pathways of interest.

Our specialised software packages allow us to conduct accurate biological interpretation and pathway analysis of genomic data. We utilise the Broad Institute Connectivity map to link gene patterns associated with disease to corresponding patterns produced by drug candidates. Additionally, we specialise in deciphering gene expression information to obtain gene expression signatures that are relevant to specific compounds, which can be used in clinical settings to monitor drug treatment.

Our commitment to quality and accuracy, combined with our state-of-the-art technology, enables us to deliver reliable and informative results that can drive your research forward. Contact us today to learn more about our NGS services and how we can help you achieve your research goals.

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